| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 2 |
|---|
| Ligand | BDBM50506088 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1824910 (CHEMBL4324674) |
|---|
| IC50 | 0.100000±n/a nM |
|---|
| Citation |  Che, J; Song, R; Chen, B; Dong, X Targeting CXCR1/2: The medicinal potential as cancer immunotherapy agents, antagonists research highlights and challenges ahead. Eur J Med Chem185:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-X-C chemokine receptor type 2 |
|---|
| Name: | C-X-C chemokine receptor type 2 |
|---|
| Synonyms: | C-X-C chemokine receptor type 2 | CD_antigen=CD182 | CXC-R2 | CXCR-2 | CXCR2_MOUSE | Cmkar2 | Cxcr2 | GRO/MGSA receptor | Gpcr16 | High affinity interleukin-8 receptor B | IL-8R B | Il8rb |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40436.24 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_117435 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MGEFKVDKFNIEDFFSGDLDIFNYSSGMPSILPDAVPCHSENLEINSYAVVVIYVLVTLL
SLVGNSLVMLVILYNRSTCSVTDVYLLNLAIADLFFALTLPVWAASKVNGWTFGSTLCKI
FSYVKEVTFYSSVLLLACISMDRYLAIVHATSTLIQKRHLVKFVCIAMWLLSVILALPIL
ILRNPVKVNLSTLVCYEDVGNNTSRLRVVLRILPQTFGFLVPLLIMLFCYGFTLRTLFKA
HMGQKHRAMRVIFAVVLVFLLCWLPYNLVLFTDTLMRTKLIKETCERRDDIDKALNATEI
LGFLHSCLNPIIYAFIGQKFRHGLLKIMATYGLVSKEFLAKEGRPSFVSSSSANTSTTL
|
|
|
|---|
| BDBM50506088 |
|---|
| n/a |
|---|
| Name | BDBM50506088 |
|---|
| Synonyms: | CHEMBL4462143 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H30N4O5 |
|---|
| Mol. Mass. | 478.5402 |
|---|
| SMILES | [H][C@@]12CCCN1CCN(C2)C(=O)c1cccc(Nc2c(N[C@H](CC)c3ccc(C)o3)c(=O)c2=O)c1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
