| Reaction Details |
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 | Report a problem with these data |
| Target | Catechol O-methyltransferase |
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| Ligand | BDBM50058811 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_47242 (CHEMBL656649) |
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| Ki | 35000±n/a nM |
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| Citation |  Brevitt, SE; Tan, EW Synthesis and in vitro evaluation of two progressive series of bifunctional polyhydroxybenzamide catechol-O-methyltransferase inhibitors. J Med Chem40:2035-9 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Catechol O-methyltransferase |
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| Name: | Catechol O-methyltransferase |
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| Synonyms: | COMT | COMT_PIG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 20586.58 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_105412 |
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| Residue: | 186 |
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| Sequence: | KERAMHVGRKKGQIVDTVVQEQRPSVLLELGAYCGYSAVRMARLLLPSARLLTIELNPDN
AAIAQQVVDFAGLQDRVTVVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLE
ECGLLRKGTVLLADNVICPGAPDFLAHVRGCGRFECTHFSSYLEYSQMVDGLEKAVYKGP
GSPAQP
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|
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| BDBM50058811 |
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| n/a |
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| Name | BDBM50058811 |
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| Synonyms: | CHEMBL60350 | N,N'-1,6-Hexanediylbis(3,4,5-trihydroxybenzamide)Hydrate |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2O8 |
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| Mol. Mass. | 420.4132 |
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| SMILES | Oc1cc(cc(O)c1O)C(=O)NCCCCCCNC(=O)c1cc(O)c(O)c(O)c1 |
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| Structure | 
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