| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholinesterase |
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| Ligand | BDBM50059900 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_27816 (CHEMBL636706) |
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| IC50 | 100000±n/a nM |
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| Citation |  Boyle, NA; Talesa, V; Giovannini, E; Rosi, G; Norton, SJ Synthesis and study of thiocarbonate derivatives of choline as potential inhibitors of acetylcholinesterase. J Med Chem40:3009-13 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholinesterase |
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| Name: | Acetylcholinesterase |
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| Synonyms: | ACES_BOVIN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 67659.62 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 613 |
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| Sequence: | MRPPWCPLHTPSLTPPLLLLLFLIGGGAEAEGPEDPELLVMVRGGRLRGLRLMAPRGPVS
AFLGIPFAEPPVGPRRFLPPEPKRPWPGVLNATAFQSVCYQYVDTLYPGFEGTEMWNPNR
ELSEDCLYLNVWTPYPRPSSPTPVLVWIYGGGFYSGASSLDVYDGRFLTQAEGTVLVSMN
YRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVG
MHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELV
ACLRARPAQDLVDHEWRVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGV
VKDEGSYFLVYGAPGFSKDNESLISRAQFLAGVRVGVPQASDLAAEAVVLHYTDWLHPED
PARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLSWPLWMGVPHGYE
IEFIFGLPLEPSLNYTIEERTFAQRLMRYWANFARTGDPNDPRDPKAPQWPPYTAGAQQY
VSLNLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQ
FDHYSKQDRCSDL
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| BDBM50059900 |
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| n/a |
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| Name | BDBM50059900 |
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| Synonyms: | CHEMBL103959 | [2-(4-Ethyl-phenylsulfanylcarbonyloxy)-ethyl]-trimethyl-ammonium; chloride |
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| Type | Small organic molecule |
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| Emp. Form. | C14H22NO2S |
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| Mol. Mass. | 268.394 |
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| SMILES | CCc1ccc(SC(=O)OCC[N+](C)(C)C)cc1 |
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| Structure | 
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