| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM50060166 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30783 (CHEMBL645060) |
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| Ki | 40000±n/a nM |
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| Citation |  Groziak, MP; Huan, ZW; Ding, H; Meng, Z; Stevens, WC; Robinson, PD Effect of a chemical modification on the hydrated adenosine intermediate produced by adenosine deaminase and a model reaction for a potential mechanism of action of 5-aminoimidazole ribonucleotide carboxylase. J Med Chem40:3336-45 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 40910.44 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 363 |
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| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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| BDBM50060166 |
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| n/a |
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| Name | BDBM50060166 |
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| Synonyms: | CHEMBL112683 | N-[1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-imidazol-4-yl]-formamide |
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| Type | Small organic molecule |
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| Emp. Form. | C9H13N3O5 |
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| Mol. Mass. | 243.2166 |
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| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc(NC=O)c1 |
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| Structure | 
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