| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50507831 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1831754 (CHEMBL4331762) |
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| Ki | 0.550000±n/a nM |
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| Citation |  Buemi, MR; Di Fiore, A; De Luca, L; Angeli, A; Mancuso, F; Ferro, S; Monti, SM; Buonanno, M; Russo, E; De Sarro, G; De Simone, G; Supuran, CT; Gitto, R Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. Eur J Med Chem163:443-452 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50507831 |
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| n/a |
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| Name | BDBM50507831 |
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| Synonyms: | CHEMBL4554983 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19BrN2O4S |
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| Mol. Mass. | 439.323 |
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| SMILES | NS(=O)(=O)c1ccc(cc1)C(=O)N1CCC(O)(CC1)c1ccc(Br)cc1 |
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| Structure | 
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