| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50060721 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_143827 (CHEMBL748712) |
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| Ki | 4.6±n/a nM |
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| Citation |  Hipskind, PA; Lobb, KL; Nixon, JA; Britton, TC; Bruns, RF; Catlow, J; Dieckman-McGinty, DK; Gackenheimer, SL; Gitter, BD; Iyengar, S; Schober, DA; Simmons, RM; Swanson, S; Zarrinmayeh, H; Zimmerman, DM; Gehlert, DR Potent and selective 1,2,3-trisubstituted indole NPY Y-1 antagonists. J Med Chem40:3712-4 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50060721 |
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| n/a |
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| Name | BDBM50060721 |
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| Synonyms: | 2-(4-Chloro-phenoxymethyl)-1-methyl-3-(2-piperidin-1-yl-ethyl)-1H-indole | CHEMBL121799 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27ClN2O |
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| Mol. Mass. | 382.926 |
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| SMILES | Cn1c(COc2ccc(Cl)cc2)c(CCN2CCCCC2)c2ccccc12 |
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| Structure | 
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