| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vesicular acetylcholine transporter |
|---|
| Ligand | BDBM50061264 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_213558 (CHEMBL817828) |
|---|
| Ki | 30±n/a nM |
|---|
| Citation |  Efange, SM; Kamath, AP; Khare, AB; Kung, MP; Mach, RH; Parsons, SM N-hydroxyalkyl derivatives of 3 beta-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. J Med Chem40:3905-14 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vesicular acetylcholine transporter |
|---|
| Name: | Vesicular acetylcholine transporter |
|---|
| Synonyms: | SLC18A3 | Solute carrier family 18 member 3 | VACHT | VACHT_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56900.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1507628 |
|---|
| Residue: | 532 |
|---|
| Sequence: | MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY
IAHMRGGGEGPTRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPTESE
DVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFA
ARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAG
KRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTT
CNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYG
ALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSV
YAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRS
ERDVLLDEPPQGLYDAVRLRERPVSGQDGEPRSPPGPFDACEDDYNYYYTRS
|
|
|
|---|
| BDBM50061264 |
|---|
| n/a |
|---|
| Name | BDBM50061264 |
|---|
| Synonyms: | 1-(4-Bromo-phenyl)-2-(4-phenyl-piperidin-1-yl)-ethanol | CHEMBL126479 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H22BrNO |
|---|
| Mol. Mass. | 360.288 |
|---|
| SMILES | OC(CN1CCC(CC1)c1ccccc1)c1ccc(Br)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
