| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50063640 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_50037 (CHEMBL662406) |
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| IC50 | 5350±n/a nM |
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| Citation |  Padia, JK; Field, M; Hinton, J; Meecham, K; Pablo, J; Pinnock, R; Roth, BD; Singh, L; Suman-Chauhan, N; Trivedi, BK; Webdale, L Novel nonpeptide CCK-B antagonists: design and development of quinazolinone derivatives as potent, selective, and orally active CCK-B antagonists. J Med Chem41:1042-9 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49676.37 |
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| Organism: | RAT |
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| Description: | Cholecystokinin central 0 RAT::P30551 |
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| Residue: | 444 |
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| Sequence: | MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQI
LLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK
DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAAT
WCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVM
VVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQL
SSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAE
KHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEE
DGRTIRALLSRYSYSHMSTSAPPP
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| BDBM50063640 |
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| n/a |
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| Name | BDBM50063640 |
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| Synonyms: | CHEMBL9405 | N-(3-cyanobenzene)-2-[3,4-dihydro-3-[3-(1-methylethoxy)phenyl]-4-oxo-2-quinazolinyl]hydrazinecarboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C25H22N6O3 |
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| Mol. Mass. | 454.4806 |
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| SMILES | CC(C)Oc1cccc(c1)-n1c(NNC(=O)Nc2cccc(c2)C#N)nc2ccccc2c1=O |
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| Structure | 
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