| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50510012 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1839935 (CHEMBL4340150) |
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| Ki | >10000±n/a nM |
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| Citation |  Bisi, A; Mokhtar Mahmoud, A; Allará, M; Naldi, M; Belluti, F; Gobbi, S; Ligresti, A; Rampa, A Polycyclic Maleimide-based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities. ACS Med Chem Lett10:596-600 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50510012 |
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| n/a |
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| Name | BDBM50510012 |
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| Synonyms: | CHEMBL4578199 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H26ClNO2 |
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| Mol. Mass. | 407.932 |
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| SMILES | CCCCCCCN1C(=O)C2C(C3c4ccccc4C2c2ccc(Cl)cc32)C1=O |TLB:25:26:10.11:18.13,8:10:18.13:26.20,27:11:18.13:26.20,14:13:10.11:26.20,THB:21:20:10.11:18.13| |
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| Structure | 
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