| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor gamma |
|---|
| Ligand | BDBM50064255 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_196163 (CHEMBL804936) |
|---|
| EC50 | 190±n/a nM |
|---|
| Citation |  Muccio, DD; Brouillette, WJ; Breitman, TR; Taimi, M; Emanuel, PD; Zhang, X; Chen, G; Sani, BP; Venepally, P; Reddy, L; Alam, M; Simpson-Herren, L; Hill, DL Conformationally defined retinoic acid analogues. 4. Potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias. J Med Chem41:1679-87 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor gamma |
|---|
| Name: | Retinoic acid receptor gamma |
|---|
| Synonyms: | Nr1b3 | RARG_MOUSE | Rarg |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 50896.02 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_196161 |
|---|
| Residue: | 458 |
|---|
| Sequence: | MATNKERLFAPGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
MFEDDSSKPGPHPKASSEDEAPGGQGKRGQSPQPDQGP
|
|
|
|---|
| BDBM50064255 |
|---|
| n/a |
|---|
| Name | BDBM50064255 |
|---|
| Synonyms: | (2E,4Z,6Z)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid | CHEMBL43833 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H30O2 |
|---|
| Mol. Mass. | 314.4617 |
|---|
| SMILES | CCC1=C(C(C)C)\C(CCC1)=C\C(\C)=C/C=C\C(\C)=C\C(O)=O |c:2| |
|---|
| Structure | 
|
|---|
Search and Browse
