| Reaction Details |
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 | Report a problem with these data |
| Target | Prolyl 4-hydroxylase |
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| Ligand | BDBM50344962 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1840409 (CHEMBL4340708) |
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| IC50 | >500000±n/a nM |
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| Citation |  Langley, GW; Abboud, MI; Lohans, CT; Schofield, CJ Inhibition of a viral prolyl hydroxylase. Bioorg Med Chem27:2405-2412 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Prolyl 4-hydroxylase |
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| Name: | Prolyl 4-hydroxylase |
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| Synonyms: | A085R | Prolyl 4-hydroxylase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27815.10 |
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| Organism: | Paramecium bursaria Chlorella virus 1 |
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| Description: | ChEMBL_119118 |
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| Residue: | 242 |
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| Sequence: | MTNKFISYNKMETREYLLTILFVIACFMVLNLERREGFETSDRPGVCDGKYYEKIDGFLS
DIECDVLINAAIKKGLIKSEVGGATENDPIKLDPKSRNSEQTWFMPGEHEVIDKIQKKTR
EFLNSKKHCIDKYNFEDVQVARYKPGQYYYHHYDGDDCDDACPKDQRLATLMVYLKAPEE
GGGGETDFPTLKTKIKPKKGTSIFFWVADPVTRKLYKETLHAGLPVKSGEKIIANQWIRA
VK
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| BDBM50344962 |
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| n/a |
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| Name | BDBM50344962 |
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| Synonyms: | (2S)-2-HYDROXYPENTANEDIOIC ACID | CHEMBL1615211 | L-2-Hydroxyglutarate |
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| Type | Small organic molecule |
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| Emp. Form. | C5H8O5 |
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| Mol. Mass. | 148.114 |
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| SMILES | O[C@@H](CCC(O)=O)C(O)=O |r| |
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| Structure | 
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