| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
|---|
| Ligand | BDBM50064580 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_33583 (CHEMBL647134) |
|---|
| IC50 | 1±n/a nM |
|---|
| Citation |  Taverne, T; Diouf, O; Depreux, P; Poupaert, JH; Lesieur, D; Guardiola-Lemaître, B; Renard, P; Rettori, MC; Caignard, DH; Pfeiffer, B Novel benzothiazolin-2-one and benzoxazin-3-one arylpiperazine derivatives with mixed 5HT1A/D2 affinity as potential atypical antipsychotics. J Med Chem41:2010-8 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1A adrenergic receptor |
|---|
| Name: | Alpha-1A adrenergic receptor |
|---|
| Synonyms: | ADA1A_BOVIN | ADRA1A | ADRA1C | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha-1C adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51492.08 |
|---|
| Organism: | CALF |
|---|
| Description: | adrenergic Alpha1 0 CALF |
|---|
| Residue: | 466 |
|---|
| Sequence: | MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
AQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSKHTLGYTL
HAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSARMAVARDPSACT
TARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV
|
|
|
|---|
| BDBM50064580 |
|---|
| n/a |
|---|
| Name | BDBM50064580 |
|---|
| Synonyms: | 6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-3H-benzothiazol-2-one | CHEMBL292935 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H25N3O2S |
|---|
| Mol. Mass. | 383.507 |
|---|
| SMILES | COc1ccccc1N1CCN(CCCc2ccc3[nH]c(=O)sc3c2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
