| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 2, facilitated glucose transporter member 4 |
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| Ligand | BDBM50510639 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1841913 (CHEMBL4342212) |
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| EC50 | 140±n/a nM |
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| Citation |  Tsuji, T; Yamaguchi, M; Kuroyanagi, J; Furuzono, S; Konishi, M; Terayama, K; Tanaka, J; Saito, M; Kobayashi, Y Discovery of novel pyridazine derivatives as glucose transporter type 4 (GLUT4) translocation activators. Bioorg Med Chem Lett29:1785-1790 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 2, facilitated glucose transporter member 4 |
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| Name: | Solute carrier family 2, facilitated glucose transporter member 4 |
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| Synonyms: | GLUT-4 | GLUT4_RAT | Glucose transporter type 4, insulin-responsive | Glut4 | Slc2a4 | Solute carrier family 2, facilitated glucose transporter member 4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54896.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_108368 |
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| Residue: | 509 |
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| Sequence: | MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNATW
LGRQGPGGPDSIPQGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLANNVLAV
LGGALMGLANAAASYEILILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAI
VIGILVAQVLGLESMLGTATLWPLLLAITVLPALLQLLLLPFCPESPRYLYIIRNLEGPA
RKSLKRLTGWADVSDALAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQL
SGINAVFYYSTSIFELAGVEQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGM
CGCAILMTVALLLLERVPSMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAM
AVAGFSNWTCNFIVGMGFQYVADAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQIS
ATFRRTPSLLEQEVKPSTELEYLGPDEND
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| BDBM50510639 |
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| n/a |
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| Name | BDBM50510639 |
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| Synonyms: | CHEMBL4588796 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21FN4O3S |
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| Mol. Mass. | 452.501 |
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| SMILES | COCCOc1ccccc1-c1nnc(Nc2ccc(CC(N)=O)cc2F)c2ccsc12 |
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| Structure | 
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