| Reaction Details |
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 | Report a problem with these data |
| Target | Hepatocyte growth factor activator |
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| Ligand | BDBM50512105 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1847486 (CHEMBL4348027) |
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| Ki | 7.2±n/a nM |
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| Citation |  de Siqueira, LRP; de Moraes Gomes, PAT; de Lima Ferreira, LP; de Melo Ręgo, MJB; Leite, ACL Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues. Eur J Med Chem170:237-260 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hepatocyte growth factor activator |
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| Name: | Hepatocyte growth factor activator |
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| Synonyms: | HGF activator | HGFA | HGFAC | HGFA_HUMAN | Hepatocyte growth factor activator | Hepatocyte growth factor activator long chain | Hepatocyte growth factor activator short chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 70690.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109514 |
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| Residue: | 655 |
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| Sequence: | MGRWAWVPSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILV
TSVTSETPATSAPEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLH
ACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQD
PQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGT
RHTACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVAST
SASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWE
YCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHP
WLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIE
KYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGW
GHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGG
PLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS
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| BDBM50512105 |
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| n/a |
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| Name | BDBM50512105 |
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| Synonyms: | CHEMBL4587327 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H57N11O6S |
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| Mol. Mass. | 771.973 |
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| SMILES | CC[C@H](NC(C)=O)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccc(cc2s1)C(=O)NC1CCNCC1 |r| |
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| Structure | 
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