| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50067010 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_200984 (CHEMBL873113) |
|---|
| IC50 | 6.9±n/a nM |
|---|
| Citation |  Berardi, F; Santoro, S; Perrone, R; Tortorella, V; Govoni, S; Lucchi, L N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands. J Med Chem41:3940-7 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 25266.54 |
|---|
| Organism: | RAT |
|---|
| Description: | Q9R0C9 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
|
|
|
|---|
| BDBM50067010 |
|---|
| n/a |
|---|
| Name | BDBM50067010 |
|---|
| Synonyms: | 1-(3-Indan-1-yl-propyl)-3,3-dimethyl-piperidine | CHEMBL129092 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H29N |
|---|
| Mol. Mass. | 271.4403 |
|---|
| SMILES | CC1(C)CCCN(CCCC2CCc3ccccc23)C1 |
|---|
| Structure | 
|
|---|
Search and Browse
