| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50512810 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1850351 (CHEMBL4350892) |
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| Ki | 14±n/a nM |
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| Citation |  Chen, PJ; Taylor, M; Griffin, SA; Amani, A; Hayatshahi, H; Korzekwa, K; Ye, M; Mach, RH; Liu, J; Luedtke, RR; Gordon, JC; Blass, BE Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D Bioorg Med Chem Lett29:2690-2694 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50512810 |
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| n/a |
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| Name | BDBM50512810 |
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| Synonyms: | CHEMBL4565997 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N3O2S |
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| Mol. Mass. | 435.582 |
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| SMILES | Oc1ccc(cc1)N1CCN(CCCCNC(=O)c2ccc(cc2)-c2ccsc2)CC1 |
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| Structure | 
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