Ki Summary

Reaction Details

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Target

M-phase inducer phosphatase 1

Ligand

BDBM50068033

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_40087 (CHEMBL655756)

IC50

>50000±n/a nM

Citation

Peng, H; Zalkow, LH; Abraham, RT; Powis, G Novel CDC25A phosphatase inhibitors from pyrolysis of 3-alpha-azido-B-homo-6-oxa-4-cholesten-7-one on silica gel. J Med Chem41:4677-80 (1998) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

M-phase inducer phosphatase 1

Name:

M-phase inducer phosphatase 1

Synonyms:

Type:

Protein

Mol. Mass.:

59090.18

Organism:

Homo sapiens (Human)

Description:

P30304

Residue:

524

Sequence:

MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP
ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL
WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK
ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI
SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT
DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY
CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL

BDBM50068033

n/a

Name

BDBM50068033

Synonyms:

(Z)-5-[(3R,3aR,5aS,6R,9aS,9bS)-3-(1,5-Dimethyl-hexyl)-3a,6-dimethyl-8-oxo-dodecahydro-7-oxa-cyclopenta[a]naphthalen-6-yl]-pent-2-enenitrile | 5-[3-(1,5-Dimethyl-hexyl)-3a,6-dimethyl-8-oxo-dodecahydro-7-oxa-cyclopenta[a]naphthalen-6-yl]-pent-2-enenitrile | CHEMBL143666

Type

Small organic molecule

Emp. Form.

C27H43NO2

Mol. Mass.

413.6358

SMILES

CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CC(=O)O[C@](C)(CC\C=C/C#N)[C@H]3CC[C@]12C

Structure