| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50068361 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_63088 (CHEMBL676184) |
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| IC50 | 4±n/a nM |
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| Citation |  Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand. J Med Chem41:4903-9 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50068361 |
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| n/a |
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| Name | BDBM50068361 |
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| Synonyms: | 2-Methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide | CHEMBL356358 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27N3O3 |
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| Mol. Mass. | 369.4574 |
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| SMILES | COc1ccccc1N1CCN(CCNC(=O)c2ccccc2OC)CC1 |
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| Structure | 
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