| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50068455 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_200964 (CHEMBL802052) |
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| Ki | 0.32±n/a nM |
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| Citation |  Zhang, Y; Williams, W; Torrence-Campbell, C; Bowen, WD; Rice, KC Characterization of novel N,N'-disubstituted piperazines as sigma receptor ligands. J Med Chem41:4950-7 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50068455 |
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| n/a |
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| Name | BDBM50068455 |
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| Synonyms: | CHEMBL342809 | {4-Oxo-4-[4-(3-phenyl-propyl)-piperazin-1-yl]-butyl}-carbamic acid tert-butyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C22H35N3O3 |
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| Mol. Mass. | 389.5316 |
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| SMILES | CC(C)(C)OC(=O)NCCCC(=O)N1CCN(CCCc2ccccc2)CC1 |
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| Structure | 
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