| Reaction Details |
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 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 5B |
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| Ligand | BDBM50514414 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1856596 (CHEMBL4357325) |
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| IC50 | 25000±n/a nM |
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| Citation |  Bosc, D; Camberlein, V; Gealageas, R; Castillo-Aguilera, O; Deprez, B; Deprez-Poulain, R Kinetic Target-Guided Synthesis: Reaching the Age of Maturity. J Med Chem63:3817-3833 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Signal transducer and activator of transcription 5B |
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| Name: | Signal transducer and activator of transcription 5B |
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| Synonyms: | STA5B_MOUSE | Signal transducer and activator of transcription 5B | Stat5b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 89994.52 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_118975 |
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| Residue: | 786 |
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| Sequence: | MAMWIQAQQLQGDALHQMQALYGQHFPIEVRHYLSQWIESQAWDSIDLDNPQENIKATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQSTYDRCPMELVRCIRHILYNEQRLV
REANNGSSPAGSLADAMSQKHLQINQTFEELRLITQDTENELKKLQQTQEYFIIQYQESL
RIQAQFAQLGQLNPQERMSRETALQQKQVSLETWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRSDRRGAESVTEEKFTILFDSQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNI
SSNHLEDYNSMSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVYSKYYTPVPCEPATAKAADGYVKPQIKQVVPEFANASTDAGS
GATYMDQAPSPVVCPQAHYNMYPPNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQW
IPHAQS
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| BDBM50514414 |
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| n/a |
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| Name | BDBM50514414 |
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| Synonyms: | CHEMBL4439829 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H7N7O3 |
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| Mol. Mass. | 225.1649 |
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| SMILES | COC(=O)c1nonc1NCn1cnnn1 |
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| Structure | 
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