Reaction Details |
| Report a problem with these data |
Target | Proenkephalin-B |
---|
Ligand | BDBM50001465 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_98393 |
---|
Kd | 7.1±n/a nM |
---|
Citation | Han, H; Yoon, J; Janda, KD Investigations of azapeptides as mimetics of Leu-enkephalin. Bioorg Med Chem Lett8:117-20 (1999) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Proenkephalin-B |
---|
Name: | Proenkephalin-B |
Synonyms: | Alpha-neoendorphin | Beta-neoendorphin | Beta-neoendorphin-dynorphin | Big Dyn | Big dynorphin | Dyn-A17 | Dyn-B | Dynorphin A | Dynorphin A(1-13) | Dynorphin A(1-17) | Dynorphin A(1-8) | Dynorphin B | Dynorphin B(1-13) | Dynorphin B-29 | Leu-enkephalin | Leumorphin | PDYN | PDYN_HUMAN | Preprodynorphin | Proenkephalin B | Proenkephalin-B | Rimorphin |
Type: | PROTEIN |
Mol. Mass.: | 28384.36 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_98393 |
Residue: | 254 |
Sequence: | MAWQGLVLAACLLMFPSTTADCLSRCSLCAVKTQDGPKPINPLICSLQCQAALLPSEEWE
RCQSFLSFFTPSTLGLNDKEDLGSKSVGEGPYSELAKLSGSFLKELEKSKFLPSISTKEN
TLSKSLEEKLRGLSDGFREGAESELMRDAQLNDGAMETGTLYLAEEDPKEQVKRYGGFLR
KYPKRSSEVAGEGDGDSMGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRS
QEDPNAYSGELFDA
|
|
|
BDBM50001465 |
---|
n/a |
---|
Name | BDBM50001465 |
Synonyms: | (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid | ([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid | (enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid | 2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid | 2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid | 2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid | 2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid | 2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin) | 2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid | CHEMBL8234 | ENKEPHALIN | Leu-ENKEPHALIN | Leu5-Enkephalin | Tyr-Gly-Gly-Phe-Leu-OH |
Type | Small organic molecule |
Emp. Form. | C28H37N5O7 |
Mol. Mass. | 555.6227 |
SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O |
Structure |
|