| Reaction Details |
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 | Report a problem with these data |
| Target | Kynureninase |
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| Ligand | BDBM50069729 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_91725 (CHEMBL702023) |
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| IC50 | 29000±n/a nM |
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| Citation |  Drysdale, MJ; Reinhard, JF S-aryl cysteine S,S-dioxides as inhibitors of mammalian kynureninase. Bioorg Med Chem Lett8:133-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kynureninase |
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| Name: | Kynureninase |
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| Synonyms: | KYNU_RAT | Kynu |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52470.50 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_91725 |
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| Residue: | 464 |
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| Sequence: | MEPSPLELPVDAVRRIATELNCDPTDERVALRLDEEDKLKRFKDCFYIPKMRDLPSIDLS
LVNEDDNAIYFLGNSLGLQPKMVKTYLEEELDKWAKIGAYGHEVGKRPWIIGDESIVSLM
KDIVGAHEKEIALMNALTVNLHLLLLSFFKPTPKRHKILLEAKAFPSDHYAIESQIQLHG
LDVEKSMRMIKPREGEETLRMEDILEVIEKEGDSIAVVLFSGLHFYTGQLFNIPAITQAG
HAKGCFVGFDLAHAVGNVELHLHDWDVDFACWCSYKYLNSGAGGLAGAFIHEKHAHTIKP
ALVGWFGHELSTRFNMDNKLQLIPGVNGFRISNPPILLVCSLHASLEIFQQATMTALRRK
SILLTGYLEYLLKHYHGGNDTENKRPVVNIITPSRAEERGCQLTLTFSISKKGVFKELEK
RGVVCDKREPEGIRVAPVPLYNSFHDVYKFIRLLTAILDSTERN
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| BDBM50069729 |
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| n/a |
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| Name | BDBM50069729 |
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| Synonyms: | 2-Amino-3-(2-amino-3-methoxy-benzenesulfonyl)-propionic acid | CHEMBL30201 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H14N2O5S |
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| Mol. Mass. | 274.294 |
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| SMILES | COc1cccc(c1N)S(=O)(=O)CC(N)C(O)=O |
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| Structure | 
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