| Reaction Details |
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 | Report a problem with these data |
| Target | Kynureninase |
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| Ligand | BDBM50069730 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_91722 |
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| Ki | 70.0±n/a nM |
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| Citation |  Drysdale, MJ; Reinhard, JF S-aryl cysteine S,S-dioxides as inhibitors of mammalian kynureninase. Bioorg Med Chem Lett8:133-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kynureninase |
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| Name: | Kynureninase |
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| Synonyms: | KYNU | KYNU_HUMAN | L-kynurenine hydrolase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52356.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_91729 |
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| Residue: | 465 |
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| Sequence: | MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK
SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK
RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN
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| BDBM50069730 |
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| n/a |
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| Name | BDBM50069730 |
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| Synonyms: | 2-Amino-3-(2-amino-benzenesulfonyl)-propionic acid | CHEMBL280572 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12N2O4S |
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| Mol. Mass. | 244.268 |
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| SMILES | NC(CS(=O)(=O)c1ccccc1N)C(O)=O |
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| Structure | 
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