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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50514543 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1857508 (CHEMBL4358237) | ||
| Ki | 1308±n/a nM | ||
| Citation |  Kamakolanu, UG; Meyer, ME; Yasuda, D; Polgar, WE; Marti, M; Mercatelli, D; Pisaṇ, CA; Brugnoli, A; Morari, M; Zaveri, NT Discovery and Structure-Activity Relationships of Nociceptin Receptor Partial Agonists That Afford Symptom Ablation in Parkinson's Disease Models. J Med Chem63:2688-2704 (2020) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44789.51 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P35372 | ||
| Residue: | 400 | ||
| Sequence: |
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| BDBM50514543 | |||
| n/a | |||
| Name | BDBM50514543 | ||
| Synonyms: | CHEMBL4590786 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H44N4 | ||
| Mol. Mass. | 436.6758 | ||
| SMILES | CC(C)[C@H]1CC[C@H](CC1)N1CCC(CC1)n1cc(CN2CCC(N)CC2)c2ccccc12 |r,wD:6.9,3.2,(50.68,-46.35,;49.87,-45.03,;50.61,-43.68,;48.33,-45.08,;47.52,-43.77,;45.97,-43.81,;45.24,-45.17,;46.06,-46.48,;47.59,-46.44,;43.7,-45.23,;42.98,-46.58,;41.44,-46.63,;40.62,-45.33,;41.34,-43.96,;42.89,-43.91,;39.09,-45.38,;38.14,-44.16,;36.69,-44.69,;35.42,-43.83,;34.04,-44.51,;32.77,-43.65,;31.4,-44.32,;31.28,-45.85,;29.9,-46.52,;32.56,-46.71,;33.94,-46.04,;36.75,-46.23,;35.65,-47.3,;36.02,-48.79,;37.5,-49.21,;38.6,-48.14,;38.23,-46.66,)| | ||
| Structure | 
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