| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium-dependent dopamine transporter |
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| Ligand | BDBM22167 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_61991 |
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| IC50 | 3.7±n/a nM |
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| Citation |  Zimmermann, K; Hengerer, B Design and synthesis of a biotinylated dopamine transporter ligand for the purification and labeling of dopaminergic neurons. Bioorg Med Chem Lett8:261-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium-dependent dopamine transporter |
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| Name: | Sodium-dependent dopamine transporter |
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| Synonyms: | DA transporter | Monoamine transporters; Norepininephrine & dopamine | SC6A3_RAT | Slc6a3 | Sodium-dependent dopamine transporter | Sodium-dependent dopamine transporter (DAT) |
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| Type: | Multi-pass membrane protein |
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| Mol. Mass.: | 68749.45 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P23977 |
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| Residue: | 619 |
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| Sequence: | MSKSKCSVGPMSSVVAPAKESNAVGPREVELILVKEQNGVQLTNSTLINPPQTPVEAQER
ETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELAL
GQFNREGAAGVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHC
NNTWNSPNCSDAHASNSSDGLGLNDTFGTTPAAEYFERGVLHLHQSRGIDDLGPPRWQLT
ACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAMDGIRAYLSVD
FYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSINSLTSFSSG
FVVFSFLGYMAQKHNVPIRDVATDGPGLIFIIYPEAIATLPLSSAWAAVFFLMLLTLGID
SAMGGMESVITGLVDEFQLLHRHRELFTLGIVLATFLLSLFCVTNGGIYVFTLLDHFAAG
TSILFGVLIEAIGVAWFYGVQQFSDDIKQMTGQRPNLYWRLCWKLVSPCFLLYVVVVSIV
TFRPPHYGAYIFPDWANALGWIIATSSMAMVPIYATYKFCSLPGSFREKLAYAITPEKDH
QLVDRGEVRQFTLRHWLLL
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| BDBM22167 |
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| n/a |
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| Name | BDBM22167 |
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| Synonyms: | 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine | CHEMBL26320 | CHEMBL434080 | GBR 12935 | GBR-12935 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H34N2O |
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| Mol. Mass. | 414.5824 |
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| SMILES | C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1 |
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| Structure | 
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