| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50069907 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1569 |
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| Ki | >1000±n/a nM |
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| Citation |  Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH New generation dopaminergic agents. 2. Discovery of 3-OH-phenoxyethylamine and 3-OH-N1-phenylpiperazine dopaminergic templates. Bioorg Med Chem Lett8:295-300 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_MOUSE | Gpcr18 | Htr1a | Serotonin 1a (5-HT1a) receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 46192.09 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q64264 |
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| Residue: | 421 |
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| Sequence: | MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGT
SFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGN
SKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
R
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| BDBM50069907 |
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| n/a |
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| Name | BDBM50069907 |
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| Synonyms: | 1-benzyl-4-(3-hydroxyphenyl)piperazine | 3-(4-Benzyl-piperazin-1-yl)-phenol | CHEMBL88365 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20N2O |
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| Mol. Mass. | 268.3535 |
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| SMILES | Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 |
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| Structure | 
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