| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50070149 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_37241 |
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| IC50 | 15±n/a nM |
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| Citation |  Weber, AE; Mathvink, RJ; Perkins, L; Hutchins, JE; Candelore, MR; Tota, L; Strader, CD; Wyvratt, MJ; Fisher, MH Potent, selective benzenesulfonamide agonists of the human beta 3 adrenergic receptor. Bioorg Med Chem Lett8:1101-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51338.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08588 |
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| Residue: | 477 |
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| Sequence: | MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
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| BDBM50070149 |
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| n/a |
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| Name | BDBM50070149 |
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| Synonyms: | 4-((3S)-3-{[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino}butyl)phenol | CHEMBL12994 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H25NO4 |
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| Mol. Mass. | 331.4061 |
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| SMILES | C[C@@H](CCc1ccc(O)cc1)NC[C@H](O)COc1ccc(O)cc1 |
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| Structure | 
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