| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
|---|
| Ligand | BDBM50070148 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_37383 (CHEMBL649973) |
|---|
| IC50 | 2000±n/a nM |
|---|
| Citation |  Weber, AE; Mathvink, RJ; Perkins, L; Hutchins, JE; Candelore, MR; Tota, L; Strader, CD; Wyvratt, MJ; Fisher, MH Potent, selective benzenesulfonamide agonists of the human beta 3 adrenergic receptor. Bioorg Med Chem Lett8:1101-6 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-1 adrenergic receptor |
|---|
| Name: | Beta-1 adrenergic receptor |
|---|
| Synonyms: | ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 51338.40 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08588 |
|---|
| Residue: | 477 |
|---|
| Sequence: | MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
|
|
|
|---|
| BDBM50070148 |
|---|
| n/a |
|---|
| Name | BDBM50070148 |
|---|
| Synonyms: | CHEMBL274807 | Cyclohexanesulfonic acid (4-{2-[(S)-2-hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenyl)-amide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H32N2O5S |
|---|
| Mol. Mass. | 448.576 |
|---|
| SMILES | O[C@@H](CNCCc1ccc(NS(=O)(=O)C2CCCCC2)cc1)COc1ccc(O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
