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TargetKappa-type opioid receptor
LigandBDBM50353747
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1859871 (CHEMBL4360727)
Ki>10000±n/a nM
Citation Dvorácskó, SKeresztes, AMollica, AStefanucci, AMacedonio, GPieretti, SZádor, FWalter, FRDeli, MAKékesi, GBánki, LTuboly, GHorváth, GTömböly, C Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors. Eur J Med Chem178:571-588 (2019) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kappa-type opioid receptor
Name:Kappa-type opioid receptor
Synonyms:Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:42744.99
Organism:Cavia porcellus (domestic guinea pig)
Description:P41144
Residue:380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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  Blast E-value cutoff:
BDBM50353747
n/a
NameBDBM50353747
Synonyms:CHEMBL561013 | JWH-018
TypeSmall organic molecule
Emp. Form.C24H23NO
Mol. Mass.341.4455
SMILESCCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
Structure
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