Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM770 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_159291 |
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IC50 | 3000±n/a nM |
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Citation | Janakiraman, MN; Watenpaugh, KD; Tomich, PK; Chong, KT; Turner, SR; Tommasi, RA; Thaisrivongs, S; Strohbach, JW Non-peptidic HIV protease inhibitors: C2-symmetry-based design of bis-sulfonamide dihydropyrones. Bioorg Med Chem Lett8:1237-42 (1999) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM770 |
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n/a |
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Name | BDBM770 |
Synonyms: | 4-hydroxy-6-(1-phenylbutan-2-yl)-3-(1-phenylpropyl)-2H-pyran-2-one | CHEMBL22164 | U-96988 |
Type | Small organic molecule |
Emp. Form. | C24H26O3 |
Mol. Mass. | 362.4614 |
SMILES | CCC(Cc1ccccc1)c1cc(O)c(C(CC)c2ccccc2)c(=O)o1 |
Structure |
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