| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM50070645 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_30791 |
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| Ki | 0.950000±n/a nM |
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| Citation |  Curtis, MA; Varkhedkar, V; Pragnacharyulu, PV; Abushanab, E Adenosine deaminase inhibitors. Synthesis and biological evaluation of aralkyladenines (ARADS). Bioorg Med Chem Lett8:1639-42 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 40910.44 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 363 |
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| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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|
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| BDBM50070645 |
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| n/a |
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| Name | BDBM50070645 |
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| Synonyms: | (2S,3R)-3-(6-Amino-purin-9-yl)-8-phenyl-octan-2-ol | 3-(6-Amino-purin-9-yl)-8-phenyl-octan-2-ol | CHEMBL43742 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H25N5O |
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| Mol. Mass. | 339.4347 |
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| SMILES | C[C@H](O)[C@@H](CCCCCc1ccccc1)n1cnc2c(N)ncnc12 |
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| Structure | 
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