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TargetMannose-6-phosphate isomerase
LigandBDBM50071525
Substrate/Competitorn/a
Meas. Tech.ChEBML_222749
IC50>200000±n/a nM
Citation Bhandari, AJones, DGSchullek, JRVo, KSchunk, CATamanaha, LLChen, DYuan, ZNeedels, MCGallop, MA Exploring structure-activity relationships around the phosphomannose isomerase inhibitor AF14049 via combinatorial synthesis. Bioorg Med Chem Lett8:2303-8 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Mannose-6-phosphate isomerase
Name:Mannose-6-phosphate isomerase
Synonyms:MANA | MPI_CANAL | PMI1
Type:PROTEIN
Mol. Mass.:48856.42
Organism:Candida albicans
Description:ChEMBL_222749
Residue:441
Sequence:
MSSEKLFRIQCGYQNYDWGKIGSSSAVAQFVHNSDPSITIDETKPYAELWMGTHPSVPSK
AIDLNNQTLRDLVTAKPQEYLGESIITKFGSSKELPFLFKVLSIEKVLSIQAHPDKKLGA
QLHAADPKNYPDDNHKPEMAIAVTDFEGFCGFKPLDQLAKTLATVPELNEIIGQELVDEF
ISGIKLPAEVGSQDDVNNRKLLQKVFGKLMNTDDDVIKQQTAKLLERTDREPQVFKDIDS
RLPELIQRLNKQFPNDIGLFCGCLLLNHVGLNKGEAMFLQAKDPHAYISGDIIECMAASD
NVVRAGFTPKFKDVKNLVEMLTYSYESVEKQKMPLQEFPRSKGDAVKSVLYDPPIAEFSV
LQTIFDKSKGGKQVIEGLNGPSIVIATNGKGTIQITGDDSTKQKIDTGYVFFVAPGSSIE
LTADSANQDQDFTTYRAFVEA
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  Blast E-value cutoff:
BDBM50071525
n/a
NameBDBM50071525
Synonyms:4-(2,4-Dichloro-phenoxy)-N-indan-2-yl-butyramide | CHEMBL76058
TypeSmall organic molecule
Emp. Form.C19H19Cl2NO2
Mol. Mass.364.266
SMILESClc1ccc(OCCCC(=O)NC2Cc3ccccc3C2)c(Cl)c1
Structure
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