| Reaction Details |
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 | Report a problem with these data |
| Target | Interleukin-5 receptor subunit alpha |
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| Ligand | BDBM50517036 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1867280 (CHEMBL4368255) |
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| IC50 | 20000±n/a nM |
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| Citation |  Boggu, PR; Kim, Y; Jung, SH Discovery of benzimidazole analogs as a novel interleukin-5 inhibitors. Eur J Med Chem181:0 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interleukin-5 receptor subunit alpha |
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| Name: | Interleukin-5 receptor subunit alpha |
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| Synonyms: | CD_antigen=CD125 | IL-5 receptor subunit alpha | IL-5R subunit alpha | IL-5R-alpha | IL-5RA | IL5RA_MOUSE | Il5r | Il5ra | Interleukin-5 receptor subunit alpha |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46998.03 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_118948 |
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| Residue: | 415 |
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| Sequence: | MVPVLLILVGALATLQADLLNHKKFLLLPPVNFTIKATGLAQVLLHWDPNPDQEQRHVDL
EYHVKINAPQEDEYDTRKTESKCVTPLHEGFAASVRTILKSSHTTLASSWVSAELKAPPG
SPGTSVTNLTCTTHTVVSSHTHLRPYQVSLRCTWLVGKDAPEDTQYFLYYRFGVLTEKCQ
EYSRDALNRNTACWFPRTFINSKGFEQLAVHINGSSKRAAIKPFDQLFSPLAIDQVNPPR
NVTVEIESNSLYIQWEKPLSAFPDHCFNYELKIYNTKNGHIQKEKLIANKFISKIDDVST
YSIQVRAAVSSPCRMPGRWGEWSQPIYVGKERKSLVEWHLIVLPTAACFVLLIFSLICRV
CHLWTRLFPPVPAPKSNIKDLPVVTEYEKPSNETKIEVVHCVEEVGFEVMGNSTF
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| BDBM50517036 |
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| n/a |
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| Name | BDBM50517036 |
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| Synonyms: | CHEMBL4475617 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25N3O2 |
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| Mol. Mass. | 303.3993 |
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| SMILES | OCCNCc1nc2c(OCC3CCCCC3)cccc2[nH]1 |
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| Structure | 
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