| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50071853 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_61186 |
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| Ki | 2.6±n/a nM |
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| Citation |  Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH New generation dopaminergic agents. 5. Heterocyclic bioisosteres that exploit the 3-OH-N1-phenylpiperazine dopaminergic template. Bioorg Med Chem Lett8:2675-80 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50071853 |
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| n/a |
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| Name | BDBM50071853 |
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| Synonyms: | 4-(4-Benzyl-piperazin-1-yl)-7-bromo-1H-indole | CHEMBL90476 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20BrN3 |
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| Mol. Mass. | 370.286 |
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| SMILES | Brc1ccc(N2CCN(Cc3ccccc3)CC2)c2cc[nH]c12 |
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| Structure | 
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