| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
|---|
| Ligand | BDBM50517247 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1867805 (CHEMBL4368780) |
|---|
| IC50 | 4.0±n/a nM |
|---|
| Citation |  Abdel-Magid, AF Lysophosphatidic Acid Receptor 1 Antagonists for the Treatment of Fibrosis. ACS Med Chem Lett10:1378-1379 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lysophosphatidic acid receptor 1 |
|---|
| Name: | Lysophosphatidic acid receptor 1 |
|---|
| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41120.55 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q92633 |
|---|
| Residue: | 364 |
|---|
| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
|
|
|
|---|
| BDBM50517247 |
|---|
| n/a |
|---|
| Name | BDBM50517247 |
|---|
| Synonyms: | CHEMBL4442789 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H29N3O6S |
|---|
| Mol. Mass. | 499.579 |
|---|
| SMILES | Cc1noc(c1CNS(=O)(=O)CCc1ccccc1)-c1ccc(O[C@H]2CCC[C@@H](C2)C(O)=O)cn1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
