| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Complement factor D |
|---|
| Ligand | BDBM50236214 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1868726 (CHEMBL4369792) |
|---|
| Ki | 500000±n/a nM |
|---|
| Citation |  Dalvit, C; Vulpetti, A Ligand-Based Fluorine NMR Screening: Principles and Applications in Drug Discovery Projects. J Med Chem62:2218-2244 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Complement factor D |
|---|
| Name: | Complement factor D |
|---|
| Synonyms: | Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 27039.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00746 |
|---|
| Residue: | 253 |
|---|
| Sequence: | MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
|
|
|
|---|
| BDBM50236214 |
|---|
| n/a |
|---|
| Name | BDBM50236214 |
|---|
| Synonyms: | CHEMBL4089211 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H15FN2O3 |
|---|
| Mol. Mass. | 338.3324 |
|---|
| SMILES | OC(=O)c1[nH]c2ccc(F)cc2c1NC(=O)C1CC1c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
