| Reaction Details |
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 | Report a problem with these data |
| Target | 4-aminobutyrate aminotransferase, mitochondrial |
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| Ligand | BDBM50082127 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1869962 (CHEMBL4371129) |
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| Ki | 6300000±n/a nM |
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| Citation |  Meanwell, NA Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design. J Med Chem61:5822-5880 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 4-aminobutyrate aminotransferase, mitochondrial |
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| Name: | 4-aminobutyrate aminotransferase, mitochondrial |
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| Synonyms: | (S)-3-amino-2-methylpropionate transaminase | 4-aminobutyrate aminotransferase, mitochondrial | ABAT | GABA aminotransferase | GABA transaminase | GABA-AT | GABA-T | GABAT | GABT_HUMAN | Gamma-amino-N-butyrate transaminase | L-AIBAT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56449.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1459248 |
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| Residue: | 500 |
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| Sequence: | MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMK
QLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQ
NASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYR
SKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPS
FDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGG
DNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMM
TGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLL
DLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVF
RDHHAHLFLNIFSDILADFK
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| BDBM50082127 |
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| n/a |
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| Name | BDBM50082127 |
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| Synonyms: | 3-(ammoniomethyl)-2,6-difluorobenzenolate | 3-Aminomethyl-2,6-difluoro-phenol | CHEMBL321931 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H7F2NO |
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| Mol. Mass. | 159.1334 |
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| SMILES | [NH3+]Cc1ccc(F)c([O-])c1F |
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| Structure | 
|
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