| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50072872 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_62886 (CHEMBL673596) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  López-Rodríguez, ML; Morcillo, MJ; Rovat, TK; Fernández, E; Vicente, B; Sanz, AM; Hernández, M; Orensanz, L Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A a J Med Chem42:36-49 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50072872 |
|---|
| n/a |
|---|
| Name | BDBM50072872 |
|---|
| Synonyms: | 1-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-3-fluoren-9-ylidene-pyrrolidine-2,5-dione | CHEMBL148126 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H24ClN3O2 |
|---|
| Mol. Mass. | 469.962 |
|---|
| SMILES | Clc1cccc(c1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#7]-2-[#6](=O)-[#6]\[#6](-[#6]-2=O)=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-[#6]-1 |
|---|
| Structure | 
|
|---|
Search and Browse
