| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50518984 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1873771 (CHEMBL4375060) |
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| Ki | 0.380189±n/a nM |
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| Citation |  Gaiser, BI; Danielsen, M; Marcher-Rørsted, E; Røpke Jørgensen, K; Wróbel, TM; Frykman, M; Johansson, H; Bräuner-Osborne, H; Gloriam, DE; Mathiesen, JM; Sejer Pedersen, D Probing the Existence of a Metastable Binding Site at the ? J Med Chem62:7806-7839 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50518984 |
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| n/a |
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| Name | BDBM50518984 |
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| Synonyms: | CHEMBL4564189 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H54N4O5 |
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| Mol. Mass. | 586.8057 |
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| SMILES | CC(C)NC[C@H](O)COc1ccccc1CCCCNC(=O)NCCCCc1ccccc1OC[C@@H](O)CNC(C)C |r| |
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| Structure | 
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