| Reaction Details |
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 | Report a problem with these data |
| Target | Short transient receptor potential channel 3 |
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| Ligand | BDBM50204544 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1875706 (CHEMBL4377100) |
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| IC50 | 4210±n/a nM |
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| Citation |  Sharma, S; Hopkins, CR Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases. J Med Chem62:7589-7602 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Short transient receptor potential channel 3 |
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| Name: | Short transient receptor potential channel 3 |
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| Synonyms: | TRP-3 | TRP3 | TRPC3 | TRPC3_HUMAN | Transient receptor protein 3 | hTrp-3 | hTrp3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96009.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107641 |
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| Residue: | 836 |
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| Sequence: | MREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDY
MGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKR
LTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDY
FCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIE
KEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLA
IKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPC
SRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTT
QFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFL
QATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSR
IAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFT
TVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINS
SYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRR
RLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQV
DKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
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| BDBM50204544 |
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| n/a |
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| Name | BDBM50204544 |
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| Synonyms: | CHEMBL262766 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H9F6N5OS |
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| Mol. Mass. | 421.32 |
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| SMILES | Cc1nnsc1C(=O)Nc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F |
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| Structure | 
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