Ki Summary

Reaction Details

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Target

Delta-type opioid receptor

Ligand

BDBM50073522

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_146338 (CHEMBL753787)

1250±n/a nM

Citation

Negri, L; Lattanzi, R; Tabacco, F; Orrù, L; Severini, C; Scolaro, B; Rocchi, R Dermorphin and deltorphin glycosylated analogues: synthesis and antinociceptive activity after systemic administration. J Med Chem42:400-4 (1999) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Delta-type opioid receptor

Name:

Delta-type opioid receptor

Synonyms:

DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1

Type:

Enzyme Catalytic Domain

Mol. Mass.:

40577.25

Organism:

MOUSE

Description:

P32300

Residue:

372

Sequence:

MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA

BDBM50073522

n/a

Name

BDBM50073522

Synonyms:

2-({1-[2-(2-{2-[2-(2-Amino-2-(4-hydroxy-phenyl)-acetylamino)-propionylamino]-3-phenyl-propionylamino}-acetylamino)-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-hydroxy-propionic acid 3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethyl ester | CHEMBL265781

Type

Small organic molecule

Emp. Form.

C46H59N7O16

Mol. Mass.

965.998

SMILES

C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

Structure