| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50519765 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1878368 (CHEMBL4379762) |
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| Ki | 17000±n/a nM |
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| Citation |  Matos, MJ; Vilar, S; Vazquez-Rodriguez, S; Kachler, S; Klotz, KN; Buccioni, M; Delogu, G; Santana, L; Uriarte, E; Borges, F Structure-Based Optimization of Coumarin hA J Med Chem63:2577-2587 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50519765 |
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| n/a |
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| Name | BDBM50519765 |
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| Synonyms: | CHEMBL4587147 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12O2 |
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| Mol. Mass. | 236.2653 |
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| SMILES | Cc1cccc2cc(-c3ccccc3)c(=O)oc12 |
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| Structure | 
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