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TargetAsialoglycoprotein receptor 1
LigandBDBM50074089
Substrate/Competitorn/a
Meas. Tech.ChEMBL_36369
Ki 200±n/a nM
Citation Sliedregt LARensen PCRump ETvan Santbrink PJBijsterbosch MKValentijn ARvan der Marel GAvan Boom JHvan Berkel TJBiessen EA Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor. J Med Chem 42:609-18 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Asialoglycoprotein receptor 1
Name:Asialoglycoprotein receptor 1
Synonyms:ASGP-R 1 | ASGPR 1 | Asgr-1 | Asgr1 | HL-1 | Hepatic lectin 1 | mHL-1
Type:PROTEIN
Mol. Mass.:32590.63
Organism:Mus musculus
Description:ChEMBL_36369
Residue:284
Sequence:
MTKDYQDFQHLDNDNDHHQLRRGPPPTPRLLQRLCSGSRLLLLSSSLSILLLVVVCVITS
QNSQLREDLLALRQNFSNLTVSTEDQVKALSTQGSSVGRKMKLVESKLEKQQKDLTEDHS
SLLLHVKQLVSDVRSLSCQMAAFRGNGSERTCCPINWVEYEGSCYWFSSSVRPWTEADKY
CQLENAHLVVVTSRDEQNFLQRHMGPLNTWIGLTDQNGPWKWVDGTDYETGFQNWRPEQP
DNWYGHGLGGGEDCAHFTTDGRWNDDVCRRPYRWVCETKLDKAN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50074089
n/a
NameBDBM50074089
Synonyms:CHEMBL2368207 | TG(20)C-Galactoside analogue
TypeSmall organic molecule
Emp. Form.C86H153N3O38
Mol. Mass.1837.1323
SMILES[H][C@@]12CC[C@H](C(C)CCCC(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CNC(=O)CCCCC(=O)NCC(=O)NC(COCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]1O)(COCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]1O)COCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]1O |t:24|
Structure
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