| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil cytosol factor 1 |
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| Ligand | BDBM50520364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1879639 (CHEMBL4381033) |
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| Kd | 504000±n/a nM |
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| Citation |  Solbak, SMØ; Zang, J; Narayanan, D; Høj, LJ; Bucciarelli, S; Softley, C; Meier, S; Langkilde, AE; Gotfredsen, CH; Sattler, M; Bach, A Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery. J Med Chem63:1156-1177 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neutrophil cytosol factor 1 |
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| Name: | Neutrophil cytosol factor 1 |
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| Synonyms: | 47 kDa autosomal chronic granulomatous disease protein | 47 kDa neutrophil oxidase factor | NCF-1 | NCF-47K | NCF1 | NCF1_HUMAN | NOXO2 | Neutrophil NADPH oxidase factor 1 | Neutrophil cytosol factor 1 | Nox organizer 2 | Nox-organizing protein 2 | SH3 and PX domain-containing protein 1A | SH3PXD1A | p47-phox |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44694.41 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_103757 |
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| Residue: | 390 |
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| Sequence: | MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPI
EAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCSTLMSLPTKISRCPHLLDFFKV
RPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTG
DVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAV
EGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPP
RRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSK
PQPAVPPRPSADLILNRCSESTKRKLASAV
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| BDBM50520364 |
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| n/a |
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| Name | BDBM50520364 |
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| Synonyms: | CHEMBL4554817 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H21N3 |
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| Mol. Mass. | 219.3259 |
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| SMILES | CN1CCCN(CC1)c1ccccc1CN |
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| Structure | 
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