| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
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| Ligand | BDBM50520462 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1880296 (CHEMBL4381690) |
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| IC50 | 840±n/a nM |
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| Citation |  Chen, WC; Simanjuntak, Y; Chu, LW; Ping, YH; Lee, YL; Lin, YL; Li, WS Benzenesulfonamide Derivatives as Calcium/Calmodulin-Dependent Protein Kinase Inhibitors and Antiviral Agents against Dengue and Zika Virus Infections. J Med Chem63:1313-1327 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium/calmodulin-dependent protein kinase type II subunit alpha |
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| Name: | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
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| Synonyms: | CAMK2A | CAMKA | CaM kinase II | CaM kinase II alpha | Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMK2a) | KCC2A_HUMAN | KIAA0968 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54093.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_25952118 |
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| Residue: | 478 |
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| Sequence: | MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEA
ISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIH
LMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH
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| BDBM50520462 |
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| n/a |
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| Name | BDBM50520462 |
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| Synonyms: | CHEMBL4515601 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27NO4S |
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| Mol. Mass. | 401.519 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)N(CCCC(=O)C1CCCC1)c1ccccc1 |
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| Structure | 
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