| Reaction Details |
|---|
 | Report a problem with these data |
| Target | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
|---|
| Ligand | BDBM50074962 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_212262 |
|---|
| IC50 | 360000±n/a nM |
|---|
| Citation |  Chen, MH; Steiner, MG; de Laszlo, SE; Patchett, AA; Anderson, MS; Hyland, SA; Onishi, HR; Silver, LL; Raetz, CR Carbohydroxamido-oxazolidines: antibacterial agents that target lipid A biosynthesis. Bioorg Med Chem Lett9:313-8 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| UDP-3-O-acyl-N-acetylglucosamine deacetylase |
|---|
| Name: | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
|---|
| Synonyms: | LPXC_ECOLI | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC) | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LxpC) | UDP-3-O-acyl-GlcNAc deacetylase | asmB | envA | lpxC |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 33952.00 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | P0A725 |
|---|
| Residue: | 305 |
|---|
| Sequence: | MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDT
MLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGI
DELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSAD
AFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKM
LDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAP
SAVLA
|
|
|
|---|
| BDBM50074962 |
|---|
| n/a |
|---|
| Name | BDBM50074962 |
|---|
| Synonyms: | (S)-2-Phenyl-4,5-dihydro-oxazole-4-carboxylic acid hydroxyamide | CHEMBL321219 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H10N2O3 |
|---|
| Mol. Mass. | 206.198 |
|---|
| SMILES | ONC(=O)[C@@H]1COC(=N1)c1ccccc1 |c:7| |
|---|
| Structure | 
|
|---|
Search and Browse
