| Reaction Details |
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 | Report a problem with these data |
| Target | Chymase |
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| Ligand | BDBM50075114 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_220724 |
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| IC50 | 13±n/a nM |
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| Citation |  Iijima, K; Katada, J; Hayashi, Y Symmetrical anhydride-type serine protease inhibitors: structure-activity relationship studies of human chymase inhibitors. Bioorg Med Chem Lett9:413-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymase |
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| Name: | Chymase |
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| Synonyms: | Alpha-chymase | CMA1 | CMA1_HUMAN | CYH | CYM | Chymase precursor | Mast cell protease I |
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| Type: | Enzyme |
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| Mol. Mass.: | 27340.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 247 |
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| Sequence: | MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNF
VLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKA
SLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD
FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWI
NQILQAN
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| BDBM50075114 |
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| n/a |
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| Name | BDBM50075114 |
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| Synonyms: | 1,1-dimethyl-2-phenylcarboxamidooctanoic anhydride | CHEMBL424453 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H48N2O5 |
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| Mol. Mass. | 564.7553 |
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| SMILES | CCCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCCC)NC(=O)c1ccccc1 |
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| Structure | 
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