| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine protease 1 |
|---|
| Ligand | BDBM50073139 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_158244 |
|---|
| IC50 | 300±n/a nM |
|---|
| Citation |  Iijima, K; Katada, J; Hayashi, Y Symmetrical anhydride-type serine protease inhibitors: structure-activity relationship studies of human chymase inhibitors. Bioorg Med Chem Lett9:413-8 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine protease 1 |
|---|
| Name: | Serine protease 1 |
|---|
| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 26557.80 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07477 |
|---|
| Residue: | 247 |
|---|
| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
|
|
|
|---|
| BDBM50073139 |
|---|
| n/a |
|---|
| Name | BDBM50073139 |
|---|
| Synonyms: | 2-(4-cyanophenylcarboxamido)-1,1-dimethyl-4-phenylpentanoic anhydride | CHEMBL108540 | [2,2-dimethyl-3-(N-(4-cyanobenzoyl)aminoi)-5-phenylpentanoic anhydride] |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C42H42N4O5 |
|---|
| Mol. Mass. | 682.8067 |
|---|
| SMILES | CC(C)(C(CCc1ccccc1)NC(=O)c1ccc(cc1)C#N)C(=O)OC(=O)C(C)(C)C(CCc1ccccc1)NC(=O)c1ccc(cc1)C#N |
|---|
| Structure | 
|
|---|
Search and Browse
