Ki Summary

Reaction Details

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Target

4-hydroxyphenylpyruvate dioxygenase

Ligand

BDBM50075317

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_549 (CHEMBL615569)

300000±n/a nM

Citation

Lin, S; Yang, D Inhibition of 4-hydroxyphenylpyruvate dioxygenase by sethoxydim, a potent inhibitor of acetyl-coenzyme A carboxylase. Bioorg Med Chem Lett9:551-4 (1999) [PubMed]

More Info.:

Get all data from this article, Assay Method

4-hydroxyphenylpyruvate dioxygenase

Name:

4-hydroxyphenylpyruvate dioxygenase

Synonyms:

HPD | HPPD_PIG

Type:

PROTEIN

Mol. Mass.:

45064.25

Organism:

Sus scrofa

Description:

ChEMBL_541

Residue:

393

Sequence:

MTSYSDKGEKPERGRFLHFHSVTFWVGNAKQAASYYCSKIGFEPLAYKGLETGSREVVSH
VVKQDKIVFVFSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAIIVRE
EVCCAADVRGHHTPLDRARQVWEGTLVEKMTFCLDSRPQPSQTLLHRLLLSKLPKCGLEI
IDHIVGNQPDQEMESASQWYMRNLQFHRFWSVDDTQIHTEYSALRSVVMANYEESIKMPI
NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRSLRERGVEFLAVPFTYYKQLQ
EKLKSAKIRVKESIDVLEELKILVDYDEKGYLLQIFTKPMQDRPTVFLEVIQRNNHQGFG
AGNFNSLFKAFEEEQELRGNLTDTDPNGVPFRL

BDBM50075317

n/a

Name

BDBM50075317

Synonyms:

2-{1-[(E)-Ethoxyimino]-butyl}-5-(2-ethylsulfanyl-propyl)-3-hydroxy-cyclohex-2-enone | CHEMBL326563

Type

Small organic molecule

Emp. Form.

C17H29NO3S

Mol. Mass.

327.482

SMILES

CCC\C(=N/OCC)C1C(=O)CC(CC(C)SCC)CC1=O |(12.1,-2.31,;10.76,-1.55,;9.43,-2.32,;8.09,-1.55,;8.07,-.01,;9.41,.76,;9.41,2.31,;10.74,3.08,;6.76,-2.34,;5.41,-1.57,;5.41,-.02,;4.08,-2.34,;4.08,-3.89,;2.74,-4.65,;2.76,-6.2,;4.09,-6.97,;1.41,-6.97,;.08,-6.2,;-1.25,-6.98,;5.41,-4.66,;6.76,-3.89,;8.09,-4.66,)|

Structure