| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM50075363 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_58929 |
|---|
| Ki | 7±n/a nM |
|---|
| Citation |  Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands. Bioorg Med Chem Lett9:585-8 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 419 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM50075363 |
|---|
| n/a |
|---|
| Name | BDBM50075363 |
|---|
| Synonyms: | 2-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinoline | CHEMBL154286 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H17N3 |
|---|
| Mol. Mass. | 263.337 |
|---|
| SMILES | C(N1CCc2ccccc2C1)c1c[nH]c2ncccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
